Nortriptyline for neuropathic pain in adults

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Controlled-release oxycodone for neuropathic pain and fibromyalgia in adults.

Practice Pointers Chronic neuropathic pain and fibromyalgia are estimated to affect 10% of adults older than 30 years.1 Neuropathic pain is classically difficult to treat, requiring a multidisciplinary approach with pharmacologic, physical, and mental health interventions. Even with a multifaceted approach, few patients achieve appreciable pain relief (i.e., at least a 50% reduction in pain int...

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BACKGROUND Topical creams with capsaicin are used to treat pain from a wide range of chronic conditions including neuropathic pain. Following application to the skin capsaicin causes enhanced sensitivity to noxious stimuli, followed by a period with reduced sensitivity and, after repeated applications, persistent desensitisation. There is uncertainty about the efficacy and tolerability of capsa...

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Amitriptyline for neuropathic pain and fibromyalgia in adults.

BACKGROUND Amitriptyline is a tricyclic antidepressant that is widely used to treat chronic neuropathic pain (pain due to nerve damage) and fibromyalgia, and is recommended in many guidelines. These types of pain can be treated with antidepressant drugs in doses below those at which the drugs act as antidepressants. OBJECTIVES To assess the analgesic efficacy of amitriptyline for chronic neur...

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Oxycodone for neuropathic pain and fibromyalgia in adults.

BACKGROUND This review is one of a series on drugs used to treat neuropathic pain and fibromyalgia. These conditions are estimated to affect 3 to 10% of adults, and are difficult to treat. Although they probably have different aetiologies, neuropathic pain and fibromyalgia can respond to the same therapies. There have been substantial changes in the standards of evidence considered necessary fo...

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Low-concentration topical capsaicin for chronic neuropathic pain in adults.

To assess the efficacy and tolerability of topically applied low-concentration (less than 1%) capsaicin for treating chronic neuropathic pain in adults.

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2015

ISSN: 1465-1858

DOI: 10.1002/14651858.cd011209.pub2